Cytogam is a brand name for Cytomegalovirus Immunoglobulin Intravenous Human (CMV-IGIV), a type of immunoglobulin therapy derived from human plasma. It is used to prevent and treat infections caused by the Cytomegalovirus (CMV).
Cytomegalovirus Immunoglobulin Intravenous Human
ABOUT MEDICINE
Cytogam (Cytomegalovirus Immunoglobulin) is an intravenous immunoglobulin containing standardized amount of antibody to cytomegalovirus. It is indicated for the prophylaxis of cytomegalovirus disease associated with transplantation of kidney, lung, liver, pancreas and heart. In transplants of these organs other than kidney from CMV seropositive donors into seronegative recipients, prophylactic CMV-IGIV should be considered in combination with ganciclovir
STRENGTH :
- One single-dose vial (50 mg/mL).
DOSAGE:
The maximum recommended total dosage per infusion is 150 mg Ig/kg, administered according to the following schedule:
| Type of Transplant | Kidney | Liver, Pancreas, |
| Lung, Heart | ||
| Within 72 hours of transplant: | 150 mg/kg | 150 mg/kg |
| 2 weeks post transplant: | 100 mg/kg | 150 mg/kg |
| 4 weeks post transplant: | 100 mg/kg | 150 mg/kg |
| 6 weeks post transplant: | 100 mg/kg | 150 mg/kg |
| 8 weeks post transplant: | 100 mg/kg | 150 mg/kg |
| 12 weeks post transplant: | 50 mg/kg | 100 mg/kg |
| 16 weeks post transplant: | 50 mg/kg | 100 mg/kg |
Side Effects :
Difficulty breathing, swelling of the face, itching, rash, or hives. Common side effects include decreased appetite, nausea, constipation, drowsiness (sleepiness) and tiredness.
ADVERSE EFFECTS:
- Respiratory:
- Apnea,
- Acute Respiratory Distress Syndrome (ARDS),
- Transfusion Associated Lung Injury (TRALI),
- Cyanosis, hypoxemia, pulmonary edema, dyspnea, bronchospasm
- Cardiovascular:
- Cardiac arrest,
- Thromboembolism,
- vascular collapse,
- Hypotension
- Neurological:
- Coma,
- Loss of consciousness,
- Seizures,
- Tremor
- Integumentary:
- Stevens-Johnson syndrome,
- Epidermolysis,
- Erythema multiforme,
- Bullous dermatitis
STORAGE :
2-8°C
- Aseptic Meningitis Syndrome: An aseptic meningitis syndrome (AMS) has been reported to occur infrequently in association with Immune Globulin Intravenous (Human) (IGIV) treatment). The syndrome usually begins within several hours to two days following IGIV treatment. It is characterized by symptoms and signs including severe headache, nuchal rigidity, drowsiness, fever, photophobia, painful eye movements, and nausea and vomiting.
- Hemolysis: Immune Globulin Intravenous (Human) (IGIV) products can contain blood group antibodies which may act as hemolysins and induce in vivo coating of red blood cells with immunoglobulin, causing a positive direct antiglobulin reaction and, rarely, hemolysis . Hemolytic anemia can develop subsequent to IGIV therapy due to enhanced RBC sequestration.
- Transfusion-Related Acute Lung Injury (TRALI): There have been reports of noncardiogenic pulmonary edema [Transfusion-Related Acute Lung Injury (TRALI)] in patients administered IGIV . TRALI is characterized by severe respiratory distress, pulmonary edema, hypoxemia, normal left ventricular function, and fever and typically occurs within 1-6 hours after transfusion.
FAQ
What is Cytomegalovirus (CMV)?
Cytomegalovirus is a common virus that can infect people of all ages. Most people who are infected with CMV have no symptoms, but it can cause serious health problems for people with weakened immune systems, such as those with HIV/AIDS, organ transplant recipients, and newborn.
How does Cytogam work?
Cytogam contains antibodies against the Cytomegalovirus, which help the body’s immune system recognize and fight off the virus. By providing a high concentration of these antibodies, Cytogam can help prevent or treat CMV infections.
Who can use Cytogam?
Cytogam is typically prescribed for individuals who are at high risk of developing a CMV infection, such as organ transplant recipients, patients undergoing hematopoietic stem cell transplantation, and people with weakened immune systems.
How is Cytogam administered?
Cytogam is administered intravenously, meaning it is given directly into the bloodstream through a vein. The treatment typically consists of multiple infusions over a period of several weeks.
What are the potential side effects of Cytogam?
Common side effects of Cytogam include headache, fever, chills, and muscle or joint pain. More serious side effects, such as severe allergic reactions, are rare but can occur.
Is Cytogam effective in preventing CMV infections?
Clinical studies have shown that Cytogam can significantly reduce the risk of CMV infection and disease in high-risk populations, such as organ transplant recipients and patients undergoing hematopoietic stem cell transplantation.
Can Cytogam be used to treat active CMV infections?
Yes, Cytogam can be used to treat active CMV infections in certain situations, such as in patients with weakened immune systems who do not respond to or cannot tolerate antiviral medications.
What is the cost of Cytogam (Cytomegalovirus Immunoglobulin Intravenous Human) in India?
The cost of Cytogam (Cytomegalovirus Immunoglobulin Intravenous Human) in India varies as it is not locally marketed and must be imported. Pricing depends on supplier availability, import duties, and currency rates. For the latest cost details, contact 24/7QualityMeds at +91 9967979080.
How to buy Cytogam (Cytomegalovirus Immunoglobulin Intravenous Human – CMVIG IV) online in India?
To buy Cytogam (Cytomegalovirus Immunoglobulin Intravenous Human – CMVIG IV) online in India at a genuine price, reach out to 24/7QualityMeds. We guide patients through legal import procedures, verify prescriptions, source from certified suppliers and ensure safe delivery to your location.
What are the key criteria for selecting a supplier?
While selecting a supplier, we essentially ensure that the supplier holds a valid Good Distribution Practice (GDP) certificate and possesses a valid operating license. These credentials confirm that the suppliers adherence to International standards for the proper distribution of medicinal product




