Brigatinib

Generic Name/API:Brigatinib
Packaging:One carton containing one bottle of 90 mg tablets (7 count) and one bottle of 180 mg tablets (23 count)
Storage:Store at 20°C to 25°C
Dosage:90 mg orally once daily for the first 7 days; then increase to 180 mg orally once daily
Strength:Tablets: 180 mg, 90 mg, or 30 mg
Indication:ALUNBRIG is a kinase inhibitor indicated for the treatment of adult patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) as detected by an FDA-approved test

ALUNBRIG (Brigatinib) is a targeted therapy medication primarily used in the treatment of a specific type of advanced non-small cell lung cancer (NSCLC). It functions as a tyrosine kinase inhibitor (TKI), meaning it works by blocking the activity of abnormal proteins, particularly those associated with the Anaplastic Lymphoma Kinase (ALK) gene rearrangement

STRENGTH:

Tablets: 180 mg, 90 mg, or 30 mg

DOSAGE:  

 90 mg orally once daily for the first 7 days; then increase to 180 mg orally once daily. May be taken with or without food

ADVERSE  EFFECTS:

  • Interstitial Lung Disease (ILD)/Pneumonitis 
  • Hypertension 
  • Bradycardia
  • Visual Disturbance 
  • Creatine Phosphokinase (CPK) Elevation
  • Pancreatic Enzymes Elevation 
  • Hyperglycemia

STORAGE : 

(20°C to 25°C)

  1. Interstitial Lung Disease (ILD)/Pneumonitis: Monitor for new or worsening respiratory symptoms, particularly during the first week of treatment. Withhold ALUNBRIG for new or worsening respiratory symptoms and promptly evaluate for ILD/pneumonitis. Upon recovery, either dose reduce or permanently discontinue ALUNBRIG. 
  2. Hypertension: Monitor blood pressure after 2 weeks and then at least monthly during treatment. For severe hypertension, withhold ALUNBRIG, then dose reduce or permanently discontinue. 
  3. Bradycardia: Monitor heart rate and blood pressure regularly during treatment. If symptomatic, withhold ALUNBRIG, then dose reduce or permanently discontinue. 
  4. Visual Disturbance: Advise patients to report visual symptoms.  Withhold ALUNBRIG and obtain ophthalmologic evaluation, then dose reduce or permanently discontinue ALUNBRIG.

 

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FAQ

ALUNBRIG is a prescription medication used to treat adults with non-small cell lung cancer (NSCLC) that is ALK-positive (anaplastic lymphoma kinase-positive). It’s used when the cancer has spread (metastasized) and either:

  • Has not been treated with an ALK inhibitor, or
  • Has worsened after treatment with crizotinib (another ALK inhibitor).

ALUNBRIG is a tyrosine kinase inhibitor (TKI). It blocks the activity of the ALK protein that helps cancer cells grow and survive. By targeting ALK-positive cancer cells, ALUNBRIG slows or stops tumor growth.

  • ALUNBRIG is an oral tablet, taken once daily.
  • Typically, treatment starts with 90 mg once daily for the first 7 days, followed by an increase to 180 mg once daily, if tolerated.
  • Take with or without food at the same time each day.

Common side effects include:

  • Nausea, vomiting
  • Diarrhea or constipation
  • Fatigue
  • Cough or shortness of breath
  • Headache
  • Increased liver enzymes (seen in blood tests)
  • High blood pressure

Serious side effects may include:

  • Lung problems (interstitial lung disease/pneumonitis), especially within the first week
  • High blood pressure
  • Slow heart rate (bradycardia)
  • Vision problems
  • High levels of blood sugar (hyperglycemia)
  • Liver problems
  • Muscle pain or weakness

Yes. ALUNBRIG can interact with:

  • Strong CYP3A inhibitors or inducers (e.g., certain antibiotics, antifungals, or seizure medications)

Grapefruit and grapefruit juice.
Always tell your doctor about all medications and supplements you’re taking.

No. ALUNBRIG can harm an unborn baby. Avoid pregnancy during treatment and for at least 4 months after the final dose.
Do not breastfeed while taking ALUNBRIG and for at least 1 week after stopping.

The cost of alunbrig (brigatinib) tablets in India varies as it is not always locally available and often must be imported. Supplier availability, import charges, and currency fluctuations affect the final price. For the latest cost details, contact 24/7QualityMeds at +91 9967979080.

To buy alunbrig (brigatinib) tablets online in India at a genuine price, contact 24/7QualityMeds. We assist with prescription verification, legal import procedures, certified supplier sourcing, and ensure safe delivery.

While selecting a supplier, we essentially ensure that the supplier holds a valid Good Distribution Practice (GDP) certificate and possesses a valid operating license. These credentials confirm that the supplier’s adherence to international standards for the proper distribution of medicinal products.

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