Orencia is used to treat autoimmune conditions such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), and polyarticular juvenile idiopathic arthritis (JIA). It is also used to prevent acute graft-versus-host disease (aGVHD) in patients undergoing stem cell transplants.
Abatacept
Generic Name/API:Abatacept
Packaging:1 box contains 1 vial of Abatacept
Storage:Store at 2°C to 8°C
Dosage:For dosage information, please visit the General Information section.
Strength:250 mg lyophilized powder in a single-use vial for intravenous infusion. 125 mg/mL solution in a single-dose prefilled syringe.
Indication:Orencia is a prescription medication used to treat autoimmune diseases such as rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), and psoriatic arthritis (PsA). It is administered either by intravenous infusion or subcutaneous injection, depending on the treatment plan.
Orencia (Abatacept) is an immunomodulatory drug used to treat autoimmune conditions by inhibiting T-cell activation. It is indicated for the treatment of moderate to severe rheumatoid arthritis in adults, active psoriatic arthritis, and polyarticular juvenile idiopathic arthritis in children aged 2 years and older, particularly when there is an inadequate response to other disease-modifying antirheumatic drugs (DMARDs). Additionally, it is approved for the prevention of acute graft versus host disease (aGVHD) in combination with other immunosuppressants in patients undergoing hematopoietic stem cell transplantation.
Strength:
- 250 mg lyophilized powder of abtacept in a single-use vial for intravenous infusion.
- 125 mg/mL solution in a single-dose prefilled syringe.
Dosage:
The recommended dosage for Adult Rheumatoid Arthritis are as follows:
Intravenous infusion for adult patients for Rheumatoid arthritis
Intravenous infusion of Orencia should be given for 30 minutes. This IV infusion should be given at 2 and 4 weeks after 1st infusion.
| Body weight of patient | Dose | No. of vials required |
| Less than 60kg | 500mg | 2 |
| 60 – 100kg | 750mg | 3 |
| More than 100kg | 1000mg | 4 |
Subcutaneous Dosing
- 125mg of Orencia should be administered once weekly
The recommended dosage for Juvenile rheumatoid arthritis are as follows:
- Patients having age between 6 to 17 years who weigh less than 75 kg are intravenously calculated 10 mg/kg intravenously calculated based on the patient’s body weight at each administration. Pediatric patients weighing 75 kg or more should be administered Orencia following the adult intravenous dosing regimen, not to exceed a maximum dose of 1000 mg.
Storage:
- Store at 2°C to 8°C
- Protect the vials from light
- Do not freeze the prefilled syringe
- Patients who receive Orencia along with the TNF antagonist have been shown suffering from infection, therefore patients should be monitored regarding signs and symptoms of infection.
- Fatal anaphylactic reactions have been reported.
- Sepsis and pneumonia like serious infections have been reported in patients receiving Orencia.
- Live vaccines should be avoided for the patients receiving Orencia and after its discontinuation till 3 months.
FAQ
How is Orencia administered?
It can be given as an intravenous (IV) infusion in a clinic or as a subcutaneous injection (under the skin) that may be self-administered at home, depending on the form prescribed.
How often is Orencia given?
For IV infusion, it’s typically given every 4 weeks after an initial loading dose. For subcutaneous injection, it’s usually administered once a week.
Can Orencia be used with other medications?
Yes, it is often used with non-biologic DMARDs like methotrexate, but it should not be used with other biologic immunosuppressants (e.g., TNF inhibitors).
What are the key criteria for selecting a supplier?
While selecting a supplier, we essentially ensure that the supplier holds a valid Good Distribution Practice (GDP) certification and possesses a valid operating license. These credentials confirm the supplier’s adherence to international standards for the proper distribution of medicinal products.
What is the cost of Orencia (Abatacept) injection in India
The cost of orencia (abatacept) injection in India varies since it must be imported. Supplier availability, import duties, and currency fluctuations affect the final price. For the latest cost details, contact 24/7QualityMeds at +91 9967979080.
How to buy Orencia (Abatacept) injection online in India
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