Vimizim (elosulfase alfa) Archives

November 8, 2025

Vimzim is mainly composed of the most important substance known as Elosulfase Alfa. It is used to treat a rare genetic disorder known as mucopolysaccharidosis IV A (also called MPS IVA or Morquio A syndrome). According to the global record, ~1 in 150,000–250,000 births are affected with MPS IVA.

Mode of action

MPS IVA is due to the absence of an enzyme known as N-acetylgalactosamine-6-sulfatase, which plays a role in breaking down substances in the body called glycosaminoglycans (GAGs), which eventually build up in the bones and organs, causing short bones, difficulty in moving and breathing, clouding of the eyes and hearing loss. N-acetylgalactosamine-6-sulfatase in Elosulfase Alfa is the active substance present in Vimzim, which breaks down glycosaminoglycans (GAGs) in the body and stops the cells from building up randomly, resulting in reduced symptoms in patients suffering from MPS IVA.

Indications

Vimzim is indicated in patients suffering from mucopolysaccharidosis IV A (also called MPS IVA or Morquio A syndrome)

Side Effects

The common symptoms in patients taking this medicine are headache, nausea, vomiting, abdominal pain, diarrhoea, dizziness, chills, difficulty in breathing and oropharyngeal pain.

Import guidance

Elosulfase Alfa availability in India is not permitted as of the present date, but we can import into India only by the legal procedure, since it is not registered with the Central Drugs Standard Control Organisation (CDSCO) for domestic distribution.

Steps to Import Elosulfase Alfa

Send the Elosulfase Alfa request for an order on the website: To begin with, we kindly ask either the patients or their supporters to send all the therapeutic requirements, like prescriptions and the medical history of the patient since diagnosed with MPS IVA.
Form submission: Please submit the document under the Form No.12A for the permission from the Central Drugs Standard Control Organisation (CDSCO) to import Vimzim (Elosulfase Alfa) as required. Make sure to send a genuine prescription from a Registered Medical Practitioner (RMD).
Reviewing medical documents: We review all the submitted medical documents to make the import process smooth and to deliver the medicine to you for your personal medical use.
Permission to import: We start our import process for medicines when the medical sanctioning of the patient is approved by the government authorities.
Authorised Sourcing of the product: Our sourcing team coordinates with the best international marketers and finalises at the most favourable price.
Order Execution: Lastly, we take responsibility for all the shipments till the medicine reaches you.

Elosulfase Alfa Price in India

It is available in the brand name of BioMarin in the injection form as 5ml Vials. Since it is an enzyme replacement therapy, we set the Elosulfase alfa price in India according to the global standards. Also, its price keeps fluctuating depending on the weight and dosage of the patient, warehouses and government taxes.

Conclusion

If you are planning to buy Vimzim in India or check Vimzim availability, 24/7QualityMeds can provide support throughout the entire import procedure. We are committed to extending assistance in helping patients to import Elosulfase Alfa and other prescription medicines legally by maintaining transparency through all the steps. Contact us today to buy Vimzim in India, because we get the right medication at the right time.

by 24/7QualityMeds

September 30, 2025

Elosulfase alfa, marketed under the brand name Vimizim™, is a recombinant form of the enzyme N-acetylgalactosamine-6-sulfatase, manufactured by BioMarin Pharmaceutical Inc. and approved by the US FDA in 2014 for the treatment of Mucopolysaccharidosis type IVA (MPS IVA), also known as Morquio A Syndrome.

Patients with MPS IVA lack sufficient levels of N-acetylgalactosamine-6-sulfatase, leading to the accumulation of glycosaminoglycans (GAGs) in the lysosomes, which causes progressive damage to multiple tissues and organs. Vimizim (elosulfase alfa) replaces the deficient enzyme, enabling the breakdown of GAG substrates such as keratan sulfate (KS) and chondroitin-6-sulfate (C6S).

The drug is supplied in 5 mg/5 mL vials and administered at a recommended dose of 2 mg/kg once weekly, as an intravenous infusion over 3.5 to 4.5 hours.

Elosulfase alfa mimics the function of the natural human enzyme and is targeted for uptake into lysosomes through mannose-6-phosphate receptors. Inside lysosomes, the drug enhances the breakdown of stored glycosaminoglycans, thereby reducing their toxic accumulation.

In preclinical studies using human chondrocytes derived from MPS IVA patients, elosulfase alfa demonstrated significant clearance of lysosomal KS deposits.

Elosulfase alfa (Vimizim) is a life-changing therapy for patients with Morquio A Syndrome (MPS IVA). Though not locally registered, Indian patients can legally buy elosulfase alfa India through authorized import routes. By following the required documentation and regulatory steps, patients gain access to this vital treatment.

With assistance from licensed facilitators, patients and caregivers can smoothly manage the import elosulfase alfa India process. For those seeking reliable supply and updated elosulfase alfa availability India, expert support ensures timely access, transparent pricing, and authentic sourcing.

Pricing:

Elosulfase alfa price India is variable since the drug is not registered for commercial sale in India. The cost depends on the supplier, country of origin, shipping, and documentation. Patients or caregivers can buy elosulfase alfa India legally through special import channels.

Since this is a prescription-only therapy, the price quotation for Vimizim 5 mg/5 mL injection is provided upon request, after submission of valid medical documents. For updated pricing and procurement details, contact: +919967979080 or visit: 247QualityMeds.com

Import Steps:

As Vimizim (elosulfase alfa) is not commercially registered in India, it can only be accessed through the Named Patient Import Program (NPIP).

Documents required to import Vimizim (elosulfase alfa) into India:

Valid prescription from a qualified doctor.
Diagnostic reports confirming MPS IVA.
Government-issued patient ID proof.
Import permit (if applicable).

Order confirmation process:

Order is finalized only after submission of a valid prescription and necessary documents.
Once the import permit is approved, the licensed supplier arranges shipment of Vimizim from the USA, Canada, Europe, or Australia.

With these steps, patients can import elosulfase alfa India safely and legally.

Access Information:

Elosulfase alfa availability India is made possible through authorized import facilitators such as Indian Pharma Network (IPN), which assists in procuring medicines for patients under the Named Patient Supply (NPS) route.

Available in major Indian cities including Mumbai, Delhi, Kolkata, Hyderabad, Chennai, Ahmedabad, Bangalore, Pune, Chandigarh, Jaipur, Srinagar, Goa, Lucknow, and more.
Medicines are sourced only from genuine international suppliers to ensure safety and authenticity.
100% transparency in pricing and supply is guaranteed.
Prescriptions are dispensed and checked by registered pharmacists before delivery to patients.

Additionally, IPN can facilitate global delivery of Vimizim, making the drug accessible not only in India but also in overseas countries where it may not be readily available.

Elosulfase alfa (Vimizim) offers hope for patients with Morquio A Syndrome (MPS IVA) by addressing the underlying enzyme deficiency and helping improve quality of life. While it is not commercially registered in India, patients can access this therapy safely through authorized import programs. For timely access, transparent pricing, and professional assistance, patients and caregivers can buy Elosulfase alfa in India at 247QualityMeds.com.

Vimizim (Elosulfase Alfa) in India: Indications, Side Effects & Import Guidance