Elosulfase alfa, marketed under the brand name Vimizim™, is a recombinant form of the enzyme N-acetylgalactosamine-6-sulfatase, manufactured by BioMarin Pharmaceutical Inc. and approved by the US FDA in 2014 for the treatment of Mucopolysaccharidosis type IVA (MPS IVA), also known as Morquio A Syndrome.
Patients with MPS IVA lack sufficient levels of N-acetylgalactosamine-6-sulfatase, leading to the accumulation of glycosaminoglycans (GAGs) in the lysosomes, which causes progressive damage to multiple tissues and organs. Vimizim (elosulfase alfa) replaces the deficient enzyme, enabling the breakdown of GAG substrates such as keratan sulfate (KS) and chondroitin-6-sulfate (C6S).
The drug is supplied in 5 mg/5 mL vials and administered at a recommended dose of 2 mg/kg once weekly, as an intravenous infusion over 3.5 to 4.5 hours.
Elosulfase alfa mimics the function of the natural human enzyme and is targeted for uptake into lysosomes through mannose-6-phosphate receptors. Inside lysosomes, the drug enhances the breakdown of stored glycosaminoglycans, thereby reducing their toxic accumulation.
In preclinical studies using human chondrocytes derived from MPS IVA patients, elosulfase alfa demonstrated significant clearance of lysosomal KS deposits.
Elosulfase alfa (Vimizim) is a life-changing therapy for patients with Morquio A Syndrome (MPS IVA). Though not locally registered, Indian patients can legally buy elosulfase alfa India through authorized import routes. By following the required documentation and regulatory steps, patients gain access to this vital treatment.
With assistance from licensed facilitators, patients and caregivers can smoothly manage the import elosulfase alfa India process. For those seeking reliable supply and updated elosulfase alfa availability India, expert support ensures timely access, transparent pricing, and authentic sourcing.
Pricing:
Elosulfase alfa price India is variable since the drug is not registered for commercial sale in India. The cost depends on the supplier, country of origin, shipping, and documentation. Patients or caregivers can buy elosulfase alfa India legally through special import channels.
Since this is a prescription-only therapy, the price quotation for Vimizim 5 mg/5 mL injection is provided upon request, after submission of valid medical documents. For updated pricing and procurement details, contact: +919967979080 or visit: 247QualityMeds.com
Import Steps:
As Vimizim (elosulfase alfa) is not commercially registered in India, it can only be accessed through the Named Patient Import Program (NPIP).
Documents required to import Vimizim (elosulfase alfa) into India:
- Valid prescription from a qualified doctor.
- Diagnostic reports confirming MPS IVA.
- Government-issued patient ID proof.
- Import permit (if applicable).
Order confirmation process:
- Order is finalized only after submission of a valid prescription and necessary documents.
- Once the import permit is approved, the licensed supplier arranges shipment of Vimizim from the USA, Canada, Europe, or Australia.
With these steps, patients can import elosulfase alfa India safely and legally.
Access Information
Elosulfase alfa availability India is made possible through authorized import facilitators such as Indian Pharma Network (IPN), which assists in procuring medicines for patients under the Named Patient Supply (NPS) route.
- Available in major Indian cities including Mumbai, Delhi, Kolkata, Hyderabad, Chennai, Ahmedabad, Bangalore, Pune, Chandigarh, Jaipur, Srinagar, Goa, Lucknow, and more.
- Medicines are sourced only from genuine international suppliers to ensure safety and authenticity.
- 100% transparency in pricing and supply is guaranteed.
- Prescriptions are dispensed and checked by registered pharmacists before delivery to patients.
Additionally, IPN can facilitate global delivery of Vimizim, making the drug accessible not only in India but also in overseas countries where it may not be readily available.
Elosulfase alfa (Vimizim) offers hope for patients with Morquio A Syndrome (MPS IVA) by addressing the underlying enzyme deficiency and helping improve quality of life. While it is not commercially registered in India, patients can access this therapy safely through authorized import programs. For timely access, transparent pricing, and professional assistance, patients and caregivers can buy Elosulfase alfa in India at 247QualityMeds.com.