Buy Cadonilimab Injection in India

Cadonilimab

Generic Name/API:Cadonilimab
Packaging:1 vial per box
Storage:Store refrigerated at 2°C to 8°C, protected from light
Dosage:For dosage information, please check the General Information section.
Strength:125 mg (10 mL)/bottle
Indication:The specific, approved clinical indications for Cadonilimab include: Cervical Cancer: Indicated for persistent, recurrent, or metastatic cases, particularly for patients who have progressed on platinum-based chemotherapy, including as a first-line treatment in combination with chemotherapy. G/GEJ Adenocarcinoma: Approved for locally advanced unresectable or metastatic cases in combination with chemotherapy

Cadonilimab is a novel, first-in-class PD-1/CTLA-4 bi-specific immunotherapy drug. Cadonilimab was granted marketing approval by the NMPA of China for the treatment of relapsed or metastatic cervical cancer (R/M CC) patients who progressed on or after platinum-based chemotherapy malignant tumors on June 29th, 2022.

In September 2024, Cadonilimab was approved for first-line treatment of patients with locally advanced unresectable or metastatic gastric or gastroesophageal junction (G/GEJ) adenocarcinoma, in combination with fluoropyrimidine and platinum-based chemotherapy

In May 2025, Cadonilimab was approved for the first-line treatment of persistent, recurrent, or metastatic cervical cancer, in combination with platinum-based chemotherapy, with or without bevacizumab. All the above-approved indications are included in China’s latest National Reimbursement Drug List (NRDL).

STRENGTH:

125 mg (10 mL)/bottle

DOSAGE: 

Recurrent/Metastatic Cervical Cancer

  • 6 mg/kg IV infusion every 2 weeks (Q2W) until disease progression, unacceptable toxicity, or treatment discontinuation. 

First-line Gastric/Gastroesophageal Junction Adenocarcinoma

  • 10 mg/kg IV infusion every 3 weeks (Q3W).

ADVERSE REACTIONS:

  • Most common Treatment-related adverse events (TRAEs) (Any Grade, incidence ≥ 10%): ✓ anemia, 37(33.3%); ✓ hypothyroidism, 22(19.8%); ✓ alanine aminotransferase increased, 20(18.0%).
  • Most common ≥3 Grade TRAEs (incidence ≥ 1%): ✓ anemia, 6(5.4%); ✓ decreases appetite, 3(2.7%); ✓ dyspnea.
  • Most common Immune-mediated adverse events (irAEs) (Any Grade, incidence ≥ 1%): hypothyroidism, 15(13.5%); hyperthyroidism, 13(11.7%); blood thyroid stimulating hormone decreased, 4(3.6%). 
  • Most common irAEs (≥3 Grade): immune-mediated pneumonitis, 1(0.9%); hyperthyroidism, 1(0.9%); myocarditis, 1(0.9%); myositis, 1(0.9%); hepatitis, 1(0.9%); thrombocytopenia, (0.9%); diarrhea, 1(0.9%).

STORAGE: 

Store refrigerated at 2°C to 8°C , protected from light.

Immune-Related Adverse Events (irAEs): Because cadonilimab enhances the immune system, it can cause severe or fatal inflammation in various organs. This most commonly includes the lungs, liver, intestines, endocrine system and kidneys.

Symptoms to Monitor and Report

Always seek immediate medical attention if you experience any of the following toxicity warning signs:

  • Colitis (Intestines): Severe abdominal pain, diarrhea or blood in the stool.
  • Pneumonitis (Lungs): New or worsening cough, chest pain or shortness of breath.
  • Hepatitis (Liver): Yellowing of the skin or eyes (jaundice), severe nausea or dark urine.
  • Endocrinopathies: Extreme fatigue, headache, dizziness, rapid heart rate, weight changes or changes in mood/behavior.
  • Severe Skin Reactions: Rash, blistering or peeling skin

Import Cadonilimab in India through Named Patient Program

FAQ

  • What is Cadonilimab?
  • What are the targets of Cadonilimab?
  • How is Cadonilimab administered?
  • What should clinicians do if severe immune-related toxicity develops?
  • Is Cadonilimab Injection approved worldwide?
  • What is the cost of Cadonilimab Injection in India?
  • How to Buy Cadonilimab Injection online in India?
  • Can Cadonilimab Injection be imported into India?
What is Cadonilimab?

Cadonilimab is a PD-1/CTLA-4 bispecific antibody designed to simultaneously block two immune checkpoint pathways and enhance antitumor immune responses.

What are the targets of Cadonilimab?

Cadonilimab targets PD-1 (Programmed Death-1) and CTLA-4 (Cytotoxic T-Lymphocyte Antigen-4). By blocking both pathways, it helps activate T-cells and improve the body’s immune response against cancer cells.

How is Cadonilimab administered?

Cadonilimab is administered as an intravenous (IV) infusion under the supervision of qualified healthcare professionals. The dosage and treatment schedule are determined by the treating physician.

What should clinicians do if severe immune-related toxicity develops?

Treatment interruption, corticosteroids and other immunosuppressive measures may be required depending on severity and local treatment guidelines.

Is Cadonilimab Injection approved worldwide?

No, Cadonilimab Injection approvals vary by country and indication. Healthcare professionals should consult local prescribing information and regulatory authorities for the latest approval status.

What is the cost of Cadonilimab Injection in India?

The cost of Cadonilimab Injection online in India depends on dosage, sourcing and import requirements. For the latest Cadonilimab price in India, contact 24/7 QualityMeds at +91 99679 79080.

How to Buy Cadonilimab Injection online in India?

Patients can Buy Cadonilimab Injection online in India through authorized import channels such as the Named Patient Program (NPP). 24/7 QualityMeds assists with documentation, sourcing and import procedures.

Can Cadonilimab Injection be imported into India?

Yes, Cadonilimab Injection can be imported into India through legal pathways such as the Named Patient Program, subject to a valid prescription and required medical documentation.

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