Erwinase is a chemotherapy medication used to treat certain types of leukemia. It is specifically used in patients who have developed an allergic reaction to asparaginase made from Escherichia coli (E. coli).
Asparaginase Erwinia Chrysanthemi
Generic Name/API:Asparaginase Erwinia Chrysanthemi
Packaging:1 box of Erwinase contains 5 vials
Storage:Stored at 2°C to 8°C
Dosage:For dosage information, please check the General Information section.
Strength:Lyophilized powder of asparaginase erwinia chrysanthemi of 10,000 International Units per vial
Indication:Erwinase is used as part of chemotherapy regimens to treat certain types of leukemia. Unlike other forms of asparaginase made from E. coli, Erwinase is used in patients who have developed hypersensitivity or allergic reactions to E. coli-derived asparaginase.
Erwinase is indicated in the treatment for patients with acute lymphoblastic leukemia (ALL) who have developed hypersensitivity to E. coli-derived asparaginase. It is used as a substitute to ensure continuity of therapy in patients who cannot tolerate other asparaginase preparations, helping to maintain the effectiveness of multi-agent chemotherapy protocols.
Strength:
Lyophilized powder 10,000 International Units per vial
Dosage:
To substitute for a dose of pegaspargase:
- The recommended dose is 25,000 International Units/m2 administered intramuscularly three times a week (Monday/Wednesday/Friday) for six doses for each planned dose of pegaspargase.
To substitute for a dose of native E. coli asparaginase:
- The recommended dose is 25,000 International Units/m2 administered intramuscularly for each scheduled dose of native E. coli asparaginase within a treatment.
Adverse reactions:
- Serious hypersensitivity reactions, including anaphylaxis
- Pancreatitis
- Glucose intolerance
- Thrombosis and hemorrhage
Storage:
- 2°C to 8°C
- Protect from light
- Liver or pancreas problems
- Bleeding or blood clots
- High blood sugar
- Stomach issues: pain, loss of appetite, nausea, vomiting, diarrhea
- Fever, headache, tiredness, or mouth sores
FAQ
What is Erwinase used for?
Erwinase is used in the treatment of acute lymphoblastic leukemia (ALL), particularly in patients who are hypersensitive or allergic to E. coli-derived asparaginase. It is part of a broader chemotherapy regimen.
How is Erwinase administered?
Erwinase is given by a healthcare professional, either as an intramuscular (IM) injection or an intravenous (IV) infusion, usually several times a week, depending on the treatment schedule prescribed by the oncologist.
Why is Erwinase used instead of other asparaginase drugs?
Erwinase is used when a patient develops a severe allergic reaction or hypersensitivity to standard asparaginase drugs made from E. coli. It provides an alternative form that allows treatment to continue without triggering further allergic responses.
Can Erwinase cause allergic reactions?
Yes. Although Erwinase is used when there is hypersensitivity to E. coli-based products, it can also cause allergic reactions in some patients. Patient monitoring is closely recommended during and after each dose for signs of a reaction.
What is the cost of Erwinaze (Asparaginase Erwinia chrysanthemi) in India?
The cost of Erwinaze (Asparaginase Erwinia chrysanthemi) in India varies as it is not locally approved and must be imported. Factors such as supplier availability, import charges, and international currency fluctuations can affect the final price. For the latest cost details, contact 24/7QualityMeds at +91 9967979080.
How to buy Erwinaze (Asparaginase Erwinia chrysanthemi) online in India
To buy Erwinaze (Asparaginase Erwinia chrysanthemi) online in India at a genuine price, contact 24/7QualityMeds. We assist patients with legally importing the medicine and ensure safe delivery at the best possible price.
