Vemurafenib

Generic Name/API:Vemurafenib
Packaging:Single bottle of 112, 120 count
Storage:Store at 20°C–25°C
Dosage:Recommended dose: 960 mg orally twice daily taken approximately 12 hours apart with or without a meal.
Strength:Tablet: 240 mg
Indication:a groundbreaking example of targeted therapy, specifically designed to inhibit the activity of an abnormal BRAF protein caused by the V600E genetic mutation, which is found in about half of all melanoma cases and drives uncontrollable cell growth

ZELBORAF is a kinase inhibitor indicated for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E mutation as detected by an FDA-approved test . Unlike traditional chemotherapy that broadly attacks rapidly dividing cells, Zelboraf offers a more precise approach by directly blocking the mutated protein responsible for tumor progression in this specific patient population

STRENGTH: 

Tablet: 240 mg

DOSAGE:  

Recommended dose: 960 mg orally twice daily taken approximately 12 hours apart with or without a meal 

SIDE EFFECTS:

  • Skin and subcutaneous tissue disorders 
    • Rash
    • Photosensitivity reaction 
    • Alopecia 
    •  Pruritus 
    • Hyperkeratosis
  • Musculoskeletal and connective tissue disorders 
    • Arthralgia 
    • Myalgia 
    •  Pain in extremity
  • General disorders and administration site conditions
    • Fatigue
    • Edema peripheral  
    • Pyrexia 
  • Neoplasms benign, malignant and unspecified (includes cysts and polyps) 
    • Skin papilloma 
    • Cutaneous SCC
    • Seborrheic keratosis

STORAGE : 

Store at 20°C–25°C

  • New Primary Malignancies
  • Hypersensitivity Reactions
  • Dermatologic Reactions
  • QT Prolongation
  • Hepatotoxicity
  • Photosensitivity
  • Ophthalmologic Reactions
  • Radiation Sensitization and Radiation Recall
  • Renal Failure

Process to Import Medicine

FAQ

  • What is Zelboraf (vemurafenib) used for?
  • How does Zelboraf work?
  • Is a special test needed before starting Zelboraf?
  • Is Zelboraf a type of chemotherapy?
  • What are some common side effects of Zelboraf?
  • What is the cost of zelboraf (vemurafenib) tablets in India?
  • How to buy zelboraf (vemurafenib) tablets online in India?
  • What are the key criteria for selecting a supplier?
What is Zelboraf (vemurafenib) used for?

 Zelboraf is primarily used to treat adults with unresectable (cannot be removed by surgery) or metastatic (has spread to other parts of the body) melanoma, a serious type of skin cancer. It is specifically for patients whose melanoma has a particular gene mutation called BRAF V600E. It’s also approved for certain other rare cancers, like Erdheim-Chester Disease (ECD), if they also carry the BRAF V600E mutation.

How does Zelboraf work?

Zelboraf is a targeted therapy that belongs to a class of drugs called kinase inhibitors. It works by specifically blocking the activity of the abnormal BRAF V600E protein, which acts as an “on switch” for uncontrolled cell growth in certain cancers. By inhibiting this protein, Zelboraf helps to slow or stop the growth and spread of cancer cells that rely on this mutation.

Is a special test needed before starting Zelboraf?

Yes, absolutely. Before receiving Zelboraf, patients must undergo a specific test to confirm that their cancer has the BRAF V600E mutation. This is crucial because Zelboraf is designed to target this specific genetic change and will not be effective in patients whose cancer does not have this mutation.

Is Zelboraf a type of chemotherapy?

No, Zelboraf is not traditional chemotherapy. It is a targeted therapy, meaning it specifically attacks cancer cells that have the BRAF V600E mutation, while generally sparing healthy cells. This differs from conventional chemotherapy, which often affects rapidly dividing cells throughout the body, both cancerous and healthy.

What are some common side effects of Zelboraf?

Common side effects can include skin rashes, sensitivity to sunlight (photosensitivity), joint pain (arthralgia), fatigue, hair loss, and changes in liver function. Patients on Zelboraf are also at an increased risk of developing new squamous cell skin cancers, which require close monitoring and often simple removal. It’s important to discuss all potential side effects and monitoring needs with your doctor.

What is the cost of zelboraf (vemurafenib) tablets in India?

The cost of zelboraf (vemurafenib) tablets in India varies as it is not always locally approved and often must be imported. Supplier availability, import duties, and currency fluctuations can affect the final price. For the most recent cost details, contact 24/7QualityMeds at +91 9967979080.

How to buy zelboraf (vemurafenib) tablets online in India?

To buy zelboraf (vemurafenib) tablets online in India at a genuine price, contact 24/7QualityMeds. We assist with prescription verification, legal import documentation, reliable sourcing, and ensure safe delivery to your address.

What are the key criteria for selecting a supplier?

While selecting a supplier, we essentially ensure that the supplier holds a valid Good Distribution Practice (GDP) certificate and possesses a valid operating license. These credentials confirm that the suppliers adherence to International standards for the proper distribution of medicinal product

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