Cardioxane is a cardioprotective agent indicated in prevention of chronic cumulative cardiotoxicity in adult patients who are suffering from metastatic or advanced breast cancer who have priorly received anthracycline treatments.
Dexrazoxane
Generic Name/API:Dexrazoxane
Packaging:1 vial per pack
Storage:Store at 25ºC
Dosage:For dosage information, please check the General Information section.
Strength:500mg of lyophilized powder for reconstitution in a single dose vial
Indication:Cardioxane is a cardioprotective agent used to reduce the risk of heart damage associated with certain chemotherapy treatments, particularly anthracyclines such as doxorubicin and epirubicin. It is administered intravenously and acts by chelating iron, thereby limiting the formation of free radicals that contribute to cardiotoxicity.
Cardioxane is indicated for the prevention of chronic cumulative cardiotoxicity in adult patients with advanced or metastatic breast cancer who have received a prior cumulative dose of anthracyclines and continue to require treatment with these agents. It is used alongside doxorubicin or epirubicin to reduce the risk of irreversible heart damage, particularly in long-term treatment where the risk of cardiomyopathy becomes significant.
Strength:
500mg powder for solution for infusion
Dosage:
For Adults: Administer a short intravenous infusion over 15 minutes, typically about 30 minutes before the anthracycline (like doxorubicin or epirubicin).
- Use a 10:1 ratio of dexrazoxane to anthracycline:
- 500 mg/m² dexrazoxane before 50 mg/m² doxorubicin
- 600 mg/m² dexrazoxane before 60 mg/m² epirubicin
Dose should be reduced by 50% in patients with creatinine clearance values < 40 ml/min.
Adverse Reactions:
- Pyrexia
- Pain at infusion site
- Peripheral Edema
Storage:
- Store at 25ºC
- Protect from light
- Cardioxane is reported to cause myelosuppression, continuous monitoring of hematological parameters is to be performed.
- Cardioxane is reported to cause fetal harm and so it is recommended that Cardioxane is avoided in pregnant women.
FAQ
How is cardioxane administered?
Cardioxane is administered as an intravenous infusion for adult patients. The IV infusion is given for 30minutes.
What is the pack size of Cardioxane?
Cardioxane is supplied as 1 vial per pack containing 500mg of lyophilized powder for reconstitution in a single dose vial.
What are the key criteria for selecting a supplier?
While selecting a supplier, we essentially ensure that the supplier holds a valid Good Distribution Practice (GDP) certification and possesses a valid operating license. These credentials confirm the supplier’s adherence to international standards for the proper distribution of medicinal products.
What Is the Cost of Cardioxane (Dexrazoxane) in India
The cost of Cardioxane (Dexrazoxane) in India varies as it is not locally approved and must be imported. Factors such as supplier availability, import charges, and currency fluctuations affect the final price. For the latest cost details, contact 24/7QualityMeds at +91 9967979080.
How to Buy Cardioxane (Dexrazoxane) Online in India
To buy Cardioxane (Dexrazoxane) online in India at a genuine price, contact 24/7QualityMeds. We assist with prescription verification, legal import, sourcing from certified suppliers, and ensure safe delivery to your location.
