Fotivda is a prescription medication used to treat adults with advanced renal cell carcinoma (RCC)—a type of kidney cancer—that has returned or worsened after two or more previous treatments. It is a VEGFR tyrosine kinase inhibitor, which means it blocks specific proteins that promote the growth of blood vessels that supply tumors.
Tivozanib
Generic Name/API:Tivozanib
Packaging:1 bottle contains 21 capsules of Fotivda
Storage:Store at 20°C to 25°C
Dosage:1.34 mg taken orally once daily for 21 days on treatment followed by 7 days off treatment for a 28-day cycle.
Strength:1.34 mg and 0.89 mg capsules
Indication:Fotivda is an oral, once-daily tyrosine kinase inhibitor specifically targeting vascular endothelial growth factor receptors 1, 2, and 3 (VEGFR‑TKI), designed to inhibit tumor blood vessel growth in advanced kidney cancer (renal cell carcinoma, RCC) . Fotivda offers a treatment option for those whose cancer has not responded to previous treatments .
Fotivda is indicated for the treatment of adults with relapsed or refractory advanced renal cell carcinoma (RCC) who have received two or more prior systemic therapies.Fotivda is particularly suited for patients whose cancer has progressed following therapies such as immune checkpoint inhibitors and/or other tyrosine kinase inhibitors. It is used as a third-line or later-line therapy and has demonstrated efficacy in delaying disease progression by targeting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, and VEGFR-3), which are critical for tumor angiogenesis (blood vessel growth).
Strength:
1.34 mg and 0.89 mg of Capsules
Dosage:
The recommended dosage is 1.34 mg taken orally once daily for 21 days on treatment followed by 7 days off treatment for a 28-day cycle.
Side Effects :
- High blood pressure. Tivozanib can cause high blood pressure
- Diarrhoea. This treatment may cause diarrhoea
- Feeling tired. Feeling tired is a common side effect
- Loss of appetite
- Feeling sick
- Tummy pain and heartburn
- Sore mouth and throat
- Shortness of breath and cough
Storage:
Store at 20°C to 25°C
- Fotivda can cause severe hypertension and hypertensive crises. Therefore, blood pressure should be monitored continuously.
- Fotivda can cause serious cardiac failure. Periodical monitoring of patients for symptoms of cardiac failure is mandatory. It also has been observed that fotivda can cause cardiac ischemia and arterial thromboembolic events. Monitoring of patients who are with the history and also who are at risk of this disease during the treatment of fotivda.
- Fotivda can sometimes cause fatal hemorrhagic events.
- Fotivda can cause proteinuria. Before initiating the treatment with fotivda, monitoring of patients for proteinuria is necessary.
- Thyroid dysfunction can occur to the patients who are on the treatment with fotivda. Continuous and periodical monitoring for thyroid functions is essential.
FAQ
How does Fotivda work?
Fotivda targets and inhibits vascular endothelial growth factor receptors (VEGFR-1, 2, and 3). By blocking these receptors, it reduces the tumor’s ability to grow new blood vessels, thereby slowing or stopping tumor growth.
How to take Fotivda?
- Dose: Typically 1.34 mg taken once daily.
- Cycle: Take for 21 consecutive days, followed by 7 days off (28-day cycle).
- How: Swallow the capsule whole with or without food.
Is Fotivda chemotherapy?
No. Fotivda is a targeted therapy, not traditional chemotherapy. It specifically inhibits tumor blood vessel growth rather than killing all rapidly dividing cells.
What are the key criteria for selecting a supplier?
While selecting a supplier, we essentially ensure that the supplier holds a valid Good Distribution Practice (GDP) certification and possesses a valid operating license. These credentials confirm the supplier’s adherence to international standards for the proper distribution of medicinal products.
What is the cost of fotivda (tivozanib) capsules in India?
The cost of fotivda (tivozanib) capsules in India varies since it is not locally approved and must be imported. Supplier availability, import charges, and currency fluctuations can affect the final price. For the latest cost details, contact 24/7QualityMeds at +91 9967979080.
How to buy fotivda (tivozanib) capsules online in India?
To buy fotivda (tivozanib) capsules online in India at a genuine price, contact 24/7QualityMeds. We assist with legal import process, sourcing from certified manufacturers, and ensure safe delivery to your address.
