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Miglustat

Miglustat

Generic Name/API:Miglustat
Packaging:1 blister pack contains 90 capsules of 100mg Zavesca. Six blister cards of 15 capsules are supplied in each carton.
Storage:Store the cartons and blister packs of Zavesca at 20°C to 25°C
Dosage:For dosage information, please check the General Information section.
Strength:100mg capsules of Zavesca
Indication:Zavesca is an oral medication used to treat certain rare genetic disorders, most notably mild to moderate type 1 Gaucher disease in adults who cannot receive enzyme replacement therapy. It belongs to a class of drugs known as substrate reduction therapies. Zavesca helps reduce the symptoms and complications associated with the disease, such as enlarged organs, bone pain, and fatigue. It is taken by mouth, typically three times a day, and requires regular monitoring for side effects and treatment response.

Zavesca is indicated for the treatment of adult patients with mild to moderate type 1 Gaucher disease for whom enzyme replacement therapy (ERT) is not an option, either due to hypersensitivity, poor venous access, or other medical reasons. Type 1 Gaucher disease is a rare genetic disorder caused by a deficiency of the enzyme glucocerebrosidase, leading to the buildup of fatty substances in certain organs, particularly the spleen, liver, and bone marrow. Zavesca works as a substrate reduction therapy by inhibiting the enzyme glucosylceramide synthase, which reduces the production of the fatty substrate that accumulates in patients with Gaucher disease. It is used as an oral alternative when standard ERT is unsuitable or unavailable.

Strength:

100mg capsules of Zavesca

Dosage: 

100 mg capsule administered orally three times a day at regular intervals. It may be necessary to reduce the dose to one 100 mg capsule once or twice a day in some patients due to adverse reactions, such as tremor or diarrhea. 

Patients with Renal Impairment needs dosage adjustment:

  • For mild renal impairment: 100 mg capsule twice per day
  • For moderate impairment:  one 100 mg capsule per day
  • Zavesca is not recommended in patients with severe renal impairment.  

Storage: 

  • Store the cartons and blister packs of Zavesca at 20°C to 25°C 
  • Keep out of reach of children.
  • Peripheral Neuropathy has been observed in patients and due to the same, there should be a continuous neurological monitoring of patients. 
  • Tremors usually began at initial treatment therapy, dose reduction or discontinuation of treatment to the patient taking Zavesca. 
  • Reduced platelet counts were observed in patients. 

 

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FAQ

  • What is Zavesca used for?
  • How is Zavesca taken?
  • Can Zavesca cause neurological side effects?
  • Who should take Zavesca?
  • What are the key criteria for selecting a supplier?
  • What is the cost of zavesca (miglustat) capsules in India?
  • How to buy zavesca (miglustat) capsules online in India?
What is Zavesca used for?

Zavesca is used to treat adults with mild to moderate type 1 Gaucher disease who are not suitable candidates for enzyme replacement therapy (ERT).

How is Zavesca taken?

Zavesca is taken orally, typically one capsule three times a day, with or without food.

Can Zavesca cause neurological side effects?

Yes, some patients may experience tremors, dizziness, or neuropathy; any new or worsening symptoms should be reported to a healthcare provider.

Who should take Zavesca?

It is prescribed to adults with type 1 Gaucher disease who cannot receive enzyme replacement therapy due to medical or access issues.

What are the key criteria for selecting a supplier?

While selecting a supplier, we essentially ensure that the supplier holds a valid Good Distribution Practice (GDP) certification and possesses a valid operating license. These credentials confirm the supplier’s adherence to international standards for the proper distribution of medicinal products.

What is the cost of zavesca (miglustat) capsules in India?

The cost of Zavesca (Miglustat) capsules in India varies as it is not locally approved and must be imported. Factors such as supplier availability, import charges, and international currency fluctuations can affect the final price. For the latest cost details, contact 24/7QualityMeds at +91 9967979080.

How to buy zavesca (miglustat) capsules online in India?

To buy zavesca (miglustat) capsules online in India at a genuine price, contact 24/7QualityMeds. We assist patients with legally importing the medicine and ensure safe delivery at the best possible price.

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