Mitotane is indicated in the treatment of inoperable adrenal cortical carcinoma of both functional and nonfunctional types. Mitotane or Lysodren is an adrenal cytotoxic agent which can cause adrenal inhibition, apparently without cellular destruction. The exact biochemical mechanism of action is unknown. Available data suggest that the drug modifies the peripheral metabolism of steroids as well as suppresses the adrenal cortex. It ultimately leads to reduced production of adrenal corticosteroids and aids in accumulation of free cholesterol toxic to adrenal cells.
Adverse reactions include gastrointestinal disturbances like anorexia, nausea or vomiting, and diarrhea; central nervous system side effects, primarily depression as manifested by lethargy and somnolence, dizziness or vertigo; skin toxicity, et cetera. Infrequently occurring side effects involve the eye, the genitourinary, cardiovascular system; and generalized aching, hyperpyrexia, and lowered protein bound iodine.
Mitotane or Lysodren is usually present in breast- milk. Hence, women are advised not to breastfeed during treatment. Safety and effectiveness in pediatric and geriatric patients has not been established sufficiently. In few clinical studies performed with geriatric patients, no significant differences in adverse reaction occurrence. However, dose adjustments are required in consideration with the co-occurence of hepatic, renal, cardiac impairment as well as any other drug or treatment being used.
Pricing and availability:
Mitotane is not registered in India and is not readily available through local pharmacies or standard distribution networks.
Since this is a prescription-only therapy, the price quotation for mitotane is provided upon request, after submission of valid medical documents. For updated pricing and procurement details, contact us.
The price of mitotane in India may vary depending on market dynamics, supplier availability, and regulatory updates, since the drug is not registered for commercial sale in India. Cost also depends on supplier, origin country, shipping and documentation. For the most accurate and updated pricing in India, patients can contact us directly.
Pricing may also fluctuate due to GST/local taxes, exchange rates, and changes in company pricing policies.
We help patients buy mitotane (Lysodren) in India safely and legally, ensuring full regulatory compliance under the Named Patient Supply (NPS) program and providing assistance throughout the process—from document verification to final delivery.
Access:
As mitotane is not commercially registered in India, it can only be accessed through the Named Patient Import Program (NPIP). We assist patients with products like encorafenib in India by procuring medicines for patients under the Named Patient Supply (NPS) route.
Mitotane or Lysodren is available as 500 mg tablets, 100 in each bottle.
Import process:
- Request submission for your medicine
Patients or caregivers can send a request for the product by sharing prescription details and treatment requirements. - Submission of an application (Form 12A)
Submit an application in Form 12A, along with a valid prescription from a Registered Medical Practitioner (RMP). - Verification of documents
We verify the prescription and supporting medical documents to confirm eligibility for importing the drug in small quantities for personal medical use. - Permission to import
Once approval is granted by the Drugs Controller General (India), the process of importing medicines begins as per the prescription. - Sourcing the medicine
Our sourcing team connects with authorized global suppliers to find the best mitotane price in India, thus making it convenient to easily import mitotane in India and ensure authenticity before finalizing the offer. - Delivery of the medicine
After approval and confirmation, we coordinate logistics and ensure the safe, compliant, and timely delivery of the product to the patient’s location in India.
Documents Require:
To enable the product’s import to India, patients need to provide:
- A valid doctor’s prescription specifying the product name, dosage, treatment duration, and diagnosis.
- Recent medical history and test reports (preferably from the last three months), including those confirming the disease.
- Government-issued ID proof and proof of residence of the patient.
- Import permit if applicable.
Order is finalized only after submission of a valid prescription and necessary documents. Once the import permit is approved, the licensed supplier arranges shipment of Lysodren from the USA, Canada, Europe, or Australia, etc.
With these steps, patients can import Mitotane in India safely and legally. We source only from verified international suppliers to ensure authenticity and make the medicine available across major Indian cities. Every order is handled with 100% transparency, and Prescriptions are dispensed and checked by registered pharmacists before delivery to patients.
For guidance on pricing, availability, and compliant import support for Mitotane, you can connect with 24/7QualityMeds for seamless assistance.