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Datopotamab Deruxtecan

Generic Name/API:Datopotamab deruxtecan-dlnk
Packaging:100 mg single-dose vial
Storage:Store at 2° to 8°C
Dosage:The recommended dose is 6 mg/kg given as an intravenous infusion once every 3 weeks (21-day cycle) until disease progression or unacceptable toxicity.
Strength:Injection form: 100 mg lyophilized powder in a single-dose vial.
Indication:Datroway, with the key ingredient called Datopotamab deruxtecan, is a cancer medicine used to treat advanced breast cancers. Datopotamab is a monoclonal antibody (a type of protein) that targets breast cancer cells, attaching to TROP2 (a protein), resulting in activation of Deruxtecan and destruction of cancer cells.

Datroway is a Trop2-directed antibody and topoisomerase inhibitor conjugate indicated for adult patients with unresectable or metastatic, hormone receptor (HR)-positive, Human Epidermal growth factor receptor 2 (HER2)-negative (IHC 0, IHC 1+ or IHC 2+/ISH-) breast cancer who have received prior endocrine-based therapy and chemotherapy for unresectable or metastatic disease.

Strength:

Injection form: 100 mg lyophilized powder in a single-dose vial.

Dosage: 

The recommended dose is 6 mg/kg given as an intravenous infusion once every 3 weeks (21-day cycle) until disease progression or unacceptable toxicity.

Adverse Effects:  

  • Interstitial Lung Disease/Pneumonitis: Dyspnea (shortness of breath), cough, and fever.
  • Ocular Adverse Reactions: Symptoms can include dry eye, meibomian gland dysfunction, keratitis, increased lacrimation, blepharitis, conjunctivitis, and blurred vision. 
  • Stomatitis: Mouth ulcers and oral mucositis

Side Effects:

  • Stomatitis: Inflammation of the mouth’s mucous membranes.
  • Nausea, Vomiting, constipation: Digestive issues are frequent.
  • Fatigue: Feeling unusually tired.
  • Alopecia: Hair loss can occur.
  • Dry eyes: Eyes lack adequate lubrication.
  • Keratitis: Inflammation of the cornea, the clear front layer of the eye, which can cause pain, redness, blurred vision, and sensitivity to light.
  • Decreased lymphocytes, decreased neutrophils, decreased leukocytes: A low number of white blood cells.
  • Decreased hemoglobin: Decrease in red blood cell count.
  • Decreased calcium: Low levels of calcium.
  • Increased ALT (Alkaline Phosphatase), increased AST (Aspartate Aminotransferase), and increased alkaline phosphatase: Increased blood levels of liver enzyme.

Storage:

Store at (2°C to 8°C). 

  1. Lung disease (Interstitial Lung Disease (ILD) /Pneumonitis): Datroway can cause severe or fatal Interstitial Lung Disease (ILD)/Pneumonitis.
  2. Eye problem (Ocular Adverse Reactions): Datroway can cause ocular adverse reactions, including dry eye, keratitis, blepharitis, and meibomian gland dysfunction, increased lacrimation, conjunctivitis, and blurred vision.
  3. Oral problems (Stomatitis): Datroway can cause stomatitis, including mouth ulcers and oral mucositis
  4. Reproductive problems (Embro-Fetal Toxicity): Datroway can cause Fetal harm

Process to Import Medicine

FAQ

  • What is Datroway, and what does it treat?
  • How does Datroway work to fight cancer?
  • How is Datroway typically dosed and supplied?
  • What are the most common side effects of Datroway?
  • What are the serious side effects I should watch out for?
  • Can pregnant women or breastfeeding mothers take Datroway?
  • Will I need to be monitored more closely while taking Datroway?
  • What are the key criteria for selecting a supplier?
  • What are the serious side effects I should watch out for?
  • What is the price of Datroway (Datopotamab Deruxtecan) in India?
  • How to buy Datroway (Datopotamab Deruxtecan) injection online in India?
What is Datroway, and what does it treat?

Datroway (Datopotamab deruxtecan-dlnk) is a medicine used to treat adults who have triple-negative breast cancer.

How does Datroway work to fight cancer?

Datopotamab deruxtecan in Datroway is the key component. Datopotamab is a monoclonal antibody (a type of protein) that targets breast cancer cells by binding to TROP2 (a protein). When it binds to TROP2 and enters cancer cells, Deruxtecan becomes active and destroys cancer cells by blocking an enzyme (protein) called topoisomerase 1, which helps cancer cells grow.

How is Datroway typically dosed and supplied?

The recommended dosage of Datroway (Datopotamab deruxtecan-dlnk) is 6 mg/kg given as an intravenous infusion once every 3 weeks (21-day cycle) until disease progression or unacceptable toxicity. It is supplied as a 100 mg lyophilized powder in a single-dose vial. Your doctor will determine the precise dose based on your medical condition and response to treatment.

What are the most common side effects of Datroway?

Nausea, vomiting, headache, keratitis, dry eyes, constipation, fatigue, headache, decreased white blood cell and red blood cell count, decreased calcium, and increased blood levels of liver enzymes can occur.  Your doctor will provide strategies to manage these.

What are the serious side effects I should watch out for?

Serious side effects can include lung problems (Interstitial Lung Disease (ILD) /Pneumonitis), eye problems (Ocular Adverse Reactions), oral problems (stomatitis), reproductive problems (Fetal-embryo toxicity).  It’s crucial to inform the doctor immediately of any unusual symptoms 

Can pregnant women or breastfeeding mothers take Datroway?

Datroway should be avoided during pregnancy in females. Breastfeeding mothers are not advised to breastfeed during the treatment and for one month after the last dose.

Will I need to be monitored more closely while taking Datroway?

Yes, monitoring is essential. This can include regular blood tests (to check liver enzymes, red and white blood cell counts), eye tests (before starting and during treatment), and oral checkups to monitor for potential side effects.

What are the key criteria for selecting a supplier?

While selecting a supplier, we essentially ensure that the supplier holds a valid Good Distribution Practice (GDP) certificate and possesses a valid operating license. These credentials confirm the supplier’s adherence to international standards for the proper distribution of medicinal products.

What are the serious side effects I should watch out for?

Serious side effects can include lung problems (Interstitial Lung Disease (ILD) /Pneumonitis), eye problems (Ocular Adverse Reactions), oral problems (stomatitis), reproductive problems (Fetal-embryo toxicity).  It’s crucial to inform the doctor immediately of any unusual symptoms 

What is the price of Datroway (Datopotamab Deruxtecan) in India?

The price of Datroway (Datopotamab Deruxtecan) in India varies since it must generally be imported. Factors such as supplier availability, import duties, and currency rates influence pricing. For the most up-to-date cost, contact 24/7QualityMeds at +91 9967979080.

How to buy Datroway (Datopotamab Deruxtecan) injection online in India?

To buy Datroway (Datopotamab Deruxtecan) online in India at a genuine price, get in touch with 24/7QualityMeds. We assist with prescription verification, managing import compliance, sourcing from reliable suppliers, and ensuring secure delivery.

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