Sacituzumab Govitecan is considered the main element in Trodelvy, which helps in treating adult patients with Triple-negative breast cancer. It is used to treat patients with advanced stages of Triple-negative breast cancer (TNBC). India estimates that 25-31% breast cancers are TNBC.
How does Trodelvy (Sacituzumab Govitecan) work?
Sacituzumab Govitecan is a combination of two active components.
- Sacituzumab, which is a type of targeted therapy drug called a monoclonal antibody, and
- SN-38, a chemotherapy drug.
Many breast cancer cells consist of a protein named ‘Trop-2’ on their surface. This protein transmits signals to breast cancer cells that promote progression. Sacituzumab is targeted to attach to Trop-2 and blocks it from transmitting the signals further. Now the SN-38 gets activated, which is aiming directly at breast cancer cells, eventually stopping cancer-causing cells from expanding. The impact of chemotherapy causes less harm to the healthy cells of your body by acting specifically on cancer cells.
Indications:
- Unresectable locally advanced or metastatic triple-negative breast cancer (mTNBC) who have received two or more prior systemic therapies, at least one of them for metastatic disease (spreading to other parts of the body).
- Unresectable locally advanced metastatic Hormone Receptor (HR)-positive, Human Epidermal growth factor Receptor (HER2)-negative (IHC0, IHC 1+ or IHC2+/ISH-breast cancer who received endocrine-based therapy (Hormone therapy) and at least two additional therapies in the metastatic setting.
Side effects:
The common side effects of Trodelvy are mentioned below:
- Neutropenia (Low White blood cell count)
- Severe Diarrhoea
- Nausea
- Vomiting
- Hair loss
- Allergic reactions
- Fatigue
- Light-headedness
- Decreased appetite
- Difficulty in breathing
Pricing and Availability:
The Sacituzumab Govitecan is not registered yet, as the Central Drug Standard Control Organisation (CDSCO) has not approved this medicine in India. So, the availability becomes limited, and patients can order only if it is prescribed by the doctor, after which we assist patients to buy Trodelvy in India through the legal way, right from the document verification to the final delivery of the product. The Sacituzumab Govitecan price in India may vary and depend on various factors like GST/local taxes, exchange rates, and changes in pricing policies of the company.
Safe Access:
Trodelvy is supplied in the form of one vial per box. Each single-dose vial consists of 180mg of Sacituzumab Govitecan (though some documentation shows 200mg fill as a manufacturing detail).
Steps to import process:
1) Request an order for Trodelvy : The patients or their family members can forward the prescription details and course of treatment.
2) Submission of a legal form (Form No.12) : We not only help in filing the Form No. 12A but also guide you in submitting it to the Drugs Controller General (India). Alongside this, a prescription from a Registered Medical Practitioner (RMP) is required.
3) Authentication of documents includes : Our team verifies the doctor’s prescription and all the required documents to ensure that the eligibility criteria for importing Trodelvy are according to legal guidelines.
4) Permission to import the medicine : We start the import process of the medicine as we get permission from the Drugs Controller General (India).
5) Authentic Product Sourcing : Our team connects with the authorised global suppliers and makes the best possible deal for the patient
6) Shipment and Delivery of the Medicine : We manage the logistics and coordinate with shipment procurement for safe and timely delivery of the medicine by all means.
Conclusion
If you are looking for any assistance to access sacituzumab govitecanin India? Connect with us at 24/7QualityMeds to get the sacituzumab govitecan price in India and also complete the process with ease according to legal ways and reliable sources.
