Mecasermin

Mecasermin
Generic Name/API:Mecasermin
Packaging:1 box contains 1 vial of Increlex
Storage:Store in a refrigerator at 2º to 8ºC
Dosage:For dosage information, please check the General Information section.
Strength:10mg/ml of mecasermin in a multiple dose glass vial
Indication:Increlex is specifically indicated for the long-term treatment of growth failure in children with severe primary insulin-like growth factor-1 (IGF-1) deficiency or those with growth hormone (GH) gene deletion who have developed neutralizing antibodies to growth hormone. Increlex is not indicated for use in patients with secondary forms of IGF-1 deficiency or those with closed growth plates.

Increlex is a prescription medication used to treat children with severe primary insulin-like growth factor-1 (IGF-1) deficiency, an important hormone for childhood growth. Increlex is typically prescribed when growth hormone therapy is not effective due to the body’s inability to respond to growth hormone. It is administered by injection, usually twice daily, and requires close medical supervision to monitor for potential side effects. 

Strength:

10mg/ml of mecasermin is available in a multiple dose glass vial

Dosage: 

The recommended starting dose is 0.04 to 0.08 mg/kg (40 to 80 micrograms/kg) twice daily by subcutaneous injection. If well-tolerated for at least one week, the dose may be increased by 0.04 mg/kg per dose, to the maximum dose of 0.12 mg/kg given twice daily. 

  • Pain in the hip or knee, walking with a limp;
  • Low blood sugar – headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery;
  • Swollen tonsils – snoring, breathing problems during sleep, pain or fullness in the ear, hearing problems.
  • Increased pressure inside the skull – headache with vision problems, nausea, pain behind the eyes.

Adverse reactions:

  • Hypoglycemia
  • Local and systemic hypersensitivity
  • Tonsillar hypertrophy

Storage: 

  • Store increlex vials in a refrigerator at 2º to 8ºC
  • Protect from light
  • Avoid freezing of vials
  • Increlex should be taken with a meal or snack to prevent low blood sugar, with careful dose adjustment and activity restrictions until a stable, well-tolerated dose is established.
  • Hypersensitivity and allergic reactions may occur while ongoing treatment with Increlex.
  • Intracranial hypertension may occur along with it, visual changes, papilledema can occur in patients. 
  • Lymphoid tissue hypertrophy with its associated symptoms has been observed in patients. 
  • Pediatric patients with the onset of a limp or complaints of hip or knee pain during Increlex therapy should be carefully evaluated. 
  • Malignant neoplasms in pediatric patients have been observed. 

Process to Import Medicine

FAQ

Increlex is used to treat growth failure in children with severe primary IGF-1 deficiency or those who are resistant to growth hormone therapy.

Increlex should not be used in children with secondary causes of growth failure (like malnutrition), active or suspected cancer, or closed growth plates.

It is given by subcutaneous (under the skin) injection, usually twice daily, shortly before or after a meal or snack.

Do not double the next dose; simply skip the missed dose and continue with the regular schedule.

No, it is used during the growth period and typically stopped once the growth plates have closed.

While selecting a supplier, we essentially ensure that the supplier holds a valid Good Distribution Practice (GDP) certification and possesses a valid operating license. These credentials confirm the supplier’s adherence to international standards for the proper distribution of medicinal products.

The cost of Increlex (Mecasermin) injection in India varies as it is not locally approved and must be imported. Factors such as supplier availability, import charges, and international currency changes can affect the final price. For the latest cost details, contact 24/7QualityMeds at +91 9967979080.

To buy Increlex (Mecasermin) injection in India at a genuine price, contact 24/7QualityMeds. We assist patients with legal import procedures and ensure safe delivery at the best possible price.

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